Barely Significant
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Investigations of Procalcitonin, Interleukin-8 and Defensin-β in Dogs with Superficial and Deep Pyoderma.

Vet Sci · 2026 · PMC12945064 · PMID 41745977

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)
No statistically significant differences were detected between superficial and deep pyoderma for any of the biomarkers, although IL-8 showed a trend toward higher concentrations in dogs with deep pyoderma ( p = 0.07).

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