In experiments showing DHPG-induced increase in EPSC amplitude, there was a trend toward a reduction in PPR that did not reach statistical significance ( n = 5; baseline: 1.60 ± 0.66; DHPG: 1.08 ± 0.28; p = 0.059, Wilcoxon signed-rank test).
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Group I metabotropic glutamate receptors differentially modulate excitatory transmission across interneuron types in the human cortex.
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