Trametinib in Adults with Neurofibromatosis Type 1-Related Symptomatic Plexiform Neurofibromas.

Ann Neurol · 2026 · PMC12946598 · PMID 40843989

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

approached significancep = 0.051so close (0.05 < p ≤ 0.1)

Improvement on the pain subscale with an increase of 10.7 points from baseline to 12th cycle, approached significance ( p = 0.051, n = 21).

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