Time to Awaken a Forgotten Antibacterial Agent: A 10-year Nationwide Surveillance of Latamoxef Resistance in China Based on 46,716 Isolates and Establishment of Tentative Epidemiological Cut-Off Values.

Infect Drug Resist · 2026 · PMC12947658 · PMID 41768377

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a decreasing trendno p-value reported

pneumoniae (ρ = −0.76, P <0.05) among ESBL (+) Enterobacteriaceae has shown a decreasing trend over time ( Table S3 ).

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a significant trendno p-value reported

The susceptibility rates of eight Enterobacteriaceae species, ESBL (+) Enterobacteriaceae and ESBL (-) Enterobacteriaceae to latamoxef over a 10-year period were analyzed for trends using Spearman’s rank correlation, a non-parametric method that evaluates whether there was a significant trend in the susceptibility rates over time.

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