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DEL-1 is an Endogenous Senolytic Protein that Inhibits Senescence-Associated Bone Loss.

Adv Sci (Weinh) · 2026 · PMC12948198 · PMID 41556369

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Among SASP genes investigated in the same assay, Cxcl2 was significantly upregulated in Del1 KO mice, whereas a trend for increased expression of Il6 and Tgfβ1 did not reach statistical significance (Figure 3G ).

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