Barely Significant
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Effects of <sc>n</sc>-Acetyl-<sc>l</sc>-Cysteine on the Progression of Kidney Dysfunction in Acadian Variant Fanconi Syndrome: A Case Series.

Nephron · 2026 · PMC12948375 · PMID 41553940

Europe PMCDOI
1
hedged sentence
0.1300
closest p · 2.6× alpha
0.1300
boldest claim

The sentences

did not reach statistical significancep = 0.13not close (p > 0.1)
Although an exact paired sign-flip permutation test did not reach statistical significance ( p = 0.13), the consistent direction of change across patients and a CI excluding zero suggests a trend toward improved eGFR slopes following NAC.

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