Finasteride withdrawal induces anxiety-like behavior and novelty avoidance in adult male rats.

In contrast, at time point T1, while we found no differences in entries and time spent in the open arms (panel G, two‐tailed Mann–Whitney test, U = 26, p = 0.1970 and panel H, two‐tailed Mann–Whitney test, U = 33, p = 0.5289), finasteride‐treated rats showed a trend toward more entries to the closed arms (Figure 7K , two‐tailed Mann–Whitney test, U = 14, p = 0.055), suggesting a preference to less anxiogenic component of the maze.

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