Nanoscaled, Fully Automated Hydrogen/Deuterium Exchange for Analysis of Macromolecular Assemblies Reaching the MDa Scale.

Mol Cell Proteomics · 2026 · PMC12950381 · PMID 41617135

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did not reach statistical significanceno p-value reported

A clear pattern emerged with peptides in the n HDX system exhibiting up to 10% higher D-retention, though these general differences did not reach statistical significance.

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