Doxorubicin enhances adipogenesis in an FGF2-dependent manner and induces a tumour-promoting secretory phenotype.

J Bone Oncol · 2026 · PMC12950464 · PMID 41777792

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did not quite reach statistical significanceno p-value reported

The change in gene expression of PPARG with doxorubicin treatment was also decreased when FGF2 was depleted with siRNA, although these comparisons did not quite reach statistical significance ( Fig. 3F ).

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did not reach statistical significanceno p-value reported

SOS1 gene expression also showed a pattern of increased gene expression with doxorubicin treatment, however this comparison did not reach statistical significance.

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