Comparative Efficacy and Safety of Tapinarof 0.5% and 1% Cream Regimens for Atopic Dermatitis: A Network Meta-Analysis.

Dermatol Pract Concept · 2026 · PMC12952837 · PMID 41912176

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did not reach statistical significanceno p-value reported

Tapinarof 1% once daily (OR=1.89, 95% CI: 1.02–3.25, P =0.041), and tapinarof 2% twice daily (OR=1.65, 95% CI: 0.91–3.01, P =0.094) also showed favorable outcomes, although the latter did not reach statistical significance and was not a primary focus of this analysis.

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