In contrast, although a decreasing trend in spheroid area was observed in the H2452 and 211H cell lines, these changes did not reach statistical significance (Figure 9 ). 4 Discussion This study demonstrated that inhibition of VPS34 by SAR405 significantly suppressed cell viability in pleural mesothelioma cell lines.
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Effects of Autophagy Inhibition by SAR405, a Selective VPS34 Inhibitor, on Pleural Mesothelioma Cells.
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