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Mutations in ammonia transporter RhBG that impair NH<sub>3</sub>/NH<sub>4</sub> <sup>+</sup> transport in patients with chronic kidney disease.

J Physiol · 2026 · PMC12953007 · PMID 41674104

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NH 3 /NH 4 + also caused a decrease of pH i in RhBG G148R ‐expressing oocytes (slope = −6 ± 2.61, N = 8, P = 0.0990) and RhBG G148W ‐expressing oocytes (slope = −6.77 ± 3.43, N = 6, P = 0.218) but did not reach statistical significance compared to WT‐RhBG oocytes (slope = −10.8 ± 3.4, N = 10).

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