Z-DNA binding protein 1 mediates necroptotic cell death in primary murine microglia following herpes simplex virus-1 infection.

J Neurovirol · 2026 · PMC12953409 · PMID 41772241

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hedged sentence

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

approached significancep = 0.081so close (0.05 < p ≤ 0.1)

However, the rate of cell death was significantly lower for both ZBP1-expressing and ZBP1-deficient microglia, and the difference in the final percentage cell death between GSK547 treated versus untreated HSV-1(MacIntyre) infected ZBP1-deficient microglia approached significance (28.78 ± 6.42 for vehicle versus 11.16 ± 3.92 for GSK547 treated, p = 0.081, n ≥ 3).

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