Rivaroxaban Initiation Timing and Clinical Outcomes After Acute Ischemic Stroke in Patients with Non-Valvular Atrial Fibrillation: An IPTW-Based Cohort Study.

Clin Appl Thromb Hemost · 2026 · PMC12954021 · PMID 41771766

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

did not reach statistical significancep = .064so close (0.05 < p ≤ 0.1)

Achievement of mRS 0-2 showed a similar trend, reaching significance at 12 months (aOR 1.86, 95% CI 1.08-3.23, p = .027), while mRS 0-2 at 90 days did not reach statistical significance (aOR 1.80, 95% CI 0.97-3.36, p = .064).

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a possible trendno p-value reported

The interaction test suggested a possible trend toward effect modification by baseline NIHSS ( p for interaction = .068), which should be interpreted as exploratory.

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