Effect of the Arg16Gly β<sub>2</sub>-Adrenergic Receptor Polymorphism on Long-Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype-Stratified, Multicenter Study.

Allergy · 2026 · PMC12954561 · PMID 40985517

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did not reach statistical significanceno p-value reported

Lastly, some comparisons did not reach statistical significance, maybe due to the small sample size of certain groups.

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a nonsignificant trendno p-value reported

We observed a nonsignificant trend toward a higher prevalence of bronchiectasis among carriers of the Arg16 allele; however, there is currently no evidence explicitly linking the Arg16Gly polymorphism to bronchiectasis risk in severe eosinophilic asthma.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Effect of the Arg16Gly β&lt;sub&gt;2&lt;/sub&gt;-Adrenergic Receptor Polymorphism on Long-Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype-Stratified, Multicenter Study.

The sentences

Effect of the Arg16Gly β<sub>2</sub>-Adrenergic Receptor Polymorphism on Long-Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype-Stratified, Multicenter Study.