In our study, two mismatches at the A locus was independently associated with acute rejection; while it was associated with poorer graft survival in univariate Cox analysis, this effect failed to achieve significance in multivariate analysis.
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Risk Factors for Acute Rejection in Pediatric Lung Transplantation and Its Impact on Graft Failure.
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The sentences
We also observed that age under 1 year was an independent protective factor for graft failure, a trend that was present in multivariate analysis for acute rejection but failed to reach statistical significance.