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Risk Factors for Acute Rejection in Pediatric Lung Transplantation and Its Impact on Graft Failure.

Pediatr Pulmonol · 2026 · PMC12954825 · PMID 41773563

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In our study, two mismatches at the A locus was independently associated with acute rejection; while it was associated with poorer graft survival in univariate Cox analysis, this effect failed to achieve significance in multivariate analysis.

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We also observed that age under 1 year was an independent protective factor for graft failure, a trend that was present in multivariate analysis for acute rejection but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.