Real-world effectiveness and safety of upadacitinib in Japanese patients with rheumatoid arthritis: impact of age, renal function, and low-dose therapy.

BMC Rheumatol · 2026 · PMC12955292 · PMID 41634822

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did not reach statistical significanceno p-value reported

In multivariable Cox proportional hazards models adjusting for age and baseline renal function, the association between UPA dose and AE-related discontinuation was attenuated and did not reach statistical significance.

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