Adrenal adenomata displaying mild autonomous cortisol secretion: a service evaluation of cardiometabolic profile routinely screened patients.

Cardiovasc Endocrinol Metab · 2026 · PMC12956158 · PMID 41783764

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0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not quite reach statistical significanceP = 0.10so close (0.05 < p ≤ 0.1)

ONDST cortisol concentration was positively associated with CVD, although this did not quite reach statistical significance [odds ratio (OR): 1.08 per 10 nmol/l increase, 95% confidence interval (CI): 0.99–1.18, P = 0.10].

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did not reach statistical significanceno p-value reported

Although the MACS1 and MACS2 groups demonstrated numerically higher rates of cardiovascular disease (CVD) and a greater use of lipid-lowering therapy and antihypertensive treatment, compared with the ‘normal’ group, these differences did not reach statistical significance, likely reflecting subgroup sizes, particularly in MACS2.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.