Fc-gamma receptors type3A (rs396991) genotyping for predicting infliximab efficacy and immunogenicity in ulcerative colitis: An observational study of Iraqi cohort.

Medicine (Baltimore) · 2026 · PMC12956187 · PMID 41759997

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.4160

boldest claim

The sentences

marginally significantP = .050actually significant

The multivariant logistic regression analysis as demonstrated in Table 3 , that UC patients carrying the CC genotype have marginally significant increased odds (OR = 14.77, P = .050) of maintaining therapeutic IFX TL compared to the AA genotype, suggesting a favorable genetic influence on drug pharmacokinetics.

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did not reach statistical significanceP = .416not close (p > 0.1)

Although median ATI levels were higher in the AC group, this difference did not reach statistical significance ( P = .416), indicating that the increased antibody presence within this group may not correlate directly with antibody titer magnitude.

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