Single-cell multiomic atlas of healthy pediatric bone marrow reveals age-dependent differences in lineage differentiation driven by stromal signaling.

Nat Immunol · 2026 · PMC12956572 · PMID 41703319

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Cell cycle analysis showed a trend toward higher proportions of cycling LyP-B cells (S + G2/M) in YP samples than in AYA samples (median 45.2% versus 24.5%; Fig. 3g ), which might have contributed to their increased abundance.

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