Leptin in the VMH contributes to the initial overconsumption of palatable diets by rats.

Am J Physiol Endocrinol Metab · 2025 · PMC12958143 · PMID 40418155

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0.0600

closest p · 1.2× alpha

0.0600

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The sentences

did not reach statistical significanceP < 0.06so close (0.05 < p ≤ 0.1)

9 ; saporin: P < 0.0003, time: P < 0.014, and interaction: P < 0.007), but as there were no differences in sucrose or lard consumption, the difference in total energy intakes of Lep-Sap and Blk-Sap CD rats did not reach statistical significance ( Fig. 9 ; saporin: P < 0.06, time: P < 0.004, and interaction: NS).

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a nonsignificant trendP < 0.06so close (0.05 < p ≤ 0.1)

Post hoc analyses revealed a nonsignificant trend for increased food intake in HF-fed females ( day 1 , P < 0.06) and a significant increase in food intake in HF-fed males on days 1 ( P < 0.009) and 2 ( P < 0.03).

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