Transcriptomic and metabolomic analysis of metabolite changes and regulatory mechanisms associated with gonadal degeneration in yellow oil crab (Scylla paramamosain).

BMC Genomics · 2026 · PMC12958495 · PMID 41634545

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showed a trendno p-value reported

7 types of key genes involved in steroid hormone biosynthesis (such as UGT , HSD17B12 , STS , HSD3B , SULT1E1 , SRD5A1 , and CYP1A1 ) showed a trend of upregulation in GX and TSX stages.

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a decreasing trendno p-value reported

In contrast, the 23 metabolites in Cluster 2 showed a decreasing trend with gonadal degeneration, reaching the lowest levels at the TSX stage.

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