Enhanced antitumoral activity of the academic CAR-T ARI0002h against normal and low BCMA-expressing myeloma cells after incorporating a transmembrane CD28 domain.

J Immunother Cancer · 2026 · PMC12958889 · PMID 41775430

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did not reach statistical significanceno p-value reported

As seen in figure 2E,F , although most differences did not reach statistical significance, ARI2h-TM28 did not show increased exhaustion post-rechallenge and exhibited a significantly higher CD25 expression pre-rechallenge.

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