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The siderophore transporter Sit1 is involved in the uptake of caspofungin by <i>Candida albicans</i>.

Antimicrob Agents Chemother · 2026 · PMC12959105 · PMID 41609499

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Corroborating the observed gene expression profile, iron levels were significantly higher in Fe + CAS treatment compared to iron alone, and caspofungin treatment resulted in a modest increase in iron compared to the control, although this latter difference did not reach statistical significance ( Fig. 2B ).

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