Safety concerns associated with high-dose continuous infusion of cefepime among critically ill patients with mild renal impairment to augmented renal clearance at a level 1 trauma center: CEFTOX study.

Antimicrob Agents Chemother · 2026 · PMC12959160 · PMID 41677262

Europe PMC DOI

hedged sentence

0.2780

closest p · 5.6× alpha

0.2780

boldest claim

The sentences

did not reach statistical significanceP = 0.278not close (p > 0.1)

The incidence of CIN tended to be lower in patients who received a dosage adjustment (24.6% versus 35.9% in patients with no CIN), but this difference did not reach statistical significance ( P = 0.278) ( Fig. 5A ).

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