Genome-wide DNA methylation profiles and ribosomal DNA copy number at birth.

Epigenetics · 2026 · PMC12959191 · PMID 41774615

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

Despite the relatively large number of highly significant CpGs, we did not find any associations between the rDNAcn and the mean genomic CpG methylation level.

also in 132,142 other papers

nominally significantno p-value reported

In downstream analyses, the 122 rDNAcn-related CpGs revealed 31 differentially methylated regions and 253 nominally significant correlations with cord blood gene transcripts in an eQTM analysis.

also in 7,732 other papers

borderline significantno p-value reported

When using the 25 genes annotated to the DMRs, a total of 13 overrepresented pathways were identified, of which 11 were significant (p adj < 0.05), and 2 remained only borderline significant (p adj = 0.06) after FDR correction.

also in 11,409 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.