Drug-Coated Balloons Beyond In-Stent Restenosis.

Rev Cardiovasc Med · 2026 · PMC12959982 · PMID 41789339

Europe PMC DOI

hedged sentences

0.0590

closest p · 1.2× alpha

0.1800

boldest claim

The sentences

a trend towards significancep = 0.059so close (0.05 < p ≤ 0.1)

The study included 15 studies [14 non-randomized controlled trials and 1 randomized controlled trial (RCT)] that showed that DCB was associated with a lower rate of TLR when compared to patients treated with DES, even though statistical significance was not reached, there was a trend towards significance (4.3% vs 6.9%, OR = 0.71, CI 0.49–1.01, p = 0.059).

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did not reach statistical significancep = 0.18not close (p > 0.1)

At 3 years, MACE rates were significantly lower in the DCB group (10.8% vs 20.8%, p = 0.046), and TLR rates, although lower in the DCB group, did not reach statistical significance (8.8% vs 14.8%, p = 0.18) [ 25 ].

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