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Real-world outcomes of palbociclib plus endocrine therapy in elderly patients with HR+/HER2- advanced breast cancer in Japan: a subgroup analysis of the P-BRIDGE study by age group.

Breast Cancer · 2026 · PMC12960296 · PMID 41670927

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showed a trendno p-value reported
Even after this analysis, patients who started at 125 mg still showed a trend toward better outcomes, supporting the appropriateness of this starting dose in selected elderly patients.

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