FNDC5/Irisin Attenuates TGF-β-induced Fibroblast Differentiation Via AMPK/Nrf2 Signaling and Mitochondrial Stabilization in Subepithelial Fibrosis.

Inflammation · 2026 · PMC12960402 · PMID 41708900

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a decreasing trendno p-value reported

HDM-induced inflammatory cells showed a decreasing trend in the BALF inflammation profile after irisin treatment (Fig. 7 F-I).

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did not reach statistical significanceno p-value reported

In the present study, although irisin tended to reduce inflammatory cell infiltration in BALF, these changes did not reach statistical significance in some experimental settings.

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