MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes.

On the other hand, NM2-A R705H aggregates displayed a mildly significant accumulation of UNC45a, although the aggregates never grew to the size of those triggered by N93K (Fig. 8 A and B), similar to the observations reported in COS7 cells (Fig. 6 C).

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