Clinicopathologic, molecular and tumor immune microenvironment features of mismatch repair-deficient glioblastomas in Lynch syndrome: a multicenter study of 29 cases with therapeutic implications.

Acta Neuropathol Commun · 2026 · PMC12961846 · PMID 41782063

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closest p · 1.0× alpha

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The sentences

did not reach statistical significanceP > 0.05actually significant

However, the difference between IDH-wt LS-GBMs and IDH-mut astrocytomas (WHO grade 4) (mean OS: 26.6 months, 95% CI 22.4–30.8; median OS: 26.0 months, 95% CI 13.4–38.6) did not reach statistical significance ( P > 0.05).

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