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Real-world data of opicapone in patients with Parkinson's disease experiencing motor fluctuations: the OPTIMO study.

Front Neurol · 2026 · PMC12961986 · PMID 41798821

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showed a trendno p-value reported
This observation is in line with the results of a post-hoc analysis of the BIPARK I/II studies in which patients with a shorter disease evolution (duration), lower PD severity, and shorter onset time of the motor fluctuations showed a trend for greater efficacy of opicapone ( 26 ).

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