Impact of Subventricular Zone Invasion on Preoperative Cognitive Decline in Patients with Diffuse Glioma.

Neurosurgery · 2026 · PMC12962351 · PMID 40788002

Europe PMC DOI

hedged sentences

0.0690

closest p · 1.4× alpha

0.1150

boldest claim

The sentences

showed a trendP = .069so close (0.05 < p ≤ 0.1)

Regarding cognitive dysfunction, the SVZ+ patients presented with discernible deficits in language (62.5% vs 24.6%, P < .001), auditory learning (76.6% vs 56.9%, P = .029), and showed a trend toward visual learning impairments ( P = .069) compared with the SVZ− group.

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a positive trendP = .115not close (p > 0.1)

Although no longer statistically significant after adjusting for age and T2 volume, SVZ invasion still showed a positive trend of increasing the risk of having ≥4 defective domains (adjusted OR 1.99, P = .115).

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