DNA damage response profile distinguishes poor-acting gliomas with shared methylome signatures.

Neuro Oncol · 2026 · PMC12962623 · PMID 40887772

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showed a trendno p-value reported

Tumors with the highest number of G01/G05 cells were associated with the worst OS ( Figure 4h ; Q4 P = .003, HR 2.69, 95% CI 1.41-5.13) and showed a trend for unfavorable PFS with those harboring the highest number of G01/G05 cells (Q4) being associated with significantly shorter time to progression ( Figure 4i ; Q4 P = .014, HR 1.96, 95% CI 1.15-3.34).

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