Integrative epigenetic and transcriptomic profiling of whole blood and fibroblasts in Hao-Fountain syndrome.

Front Cell Dev Biol · 2026 · PMC12963275 · PMID 41799441

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nominally significantno p-value reported

Genome-wide DNA methylation profiling identifies 2,143 significant DMRs Using bumphunter (cutoff = 0.15; 100 bootstraps), we identified 2,143 nominally significant DMRs in fibroblasts, comprising 1,314 (61.3%) hypermethylated and 829 (38.7%) hypomethylated regions.

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