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Combinational Inhibition of the eIF4F Complex, AKT1, and EZH2 Enhances Anticancer Effects in BRAF<sup>V600E</sup> Mutant A375 Melanoma Cells.

Oncol Res · 2026 · PMC12963650 · PMID 41799498

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In contrast, silencing c-Myc or c-Jun only partially inhibited apoptosis, and these effects did not reach statistical significance ( Fig. 6E ).

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