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Lifestyle factors and DNA methylation-based aging clocks: cross-sectional and longitudinal associations in the Singapore diet and healthy aging cohort.

J Prev Alzheimers Dis · 2026 · PMC12964021 · PMID 41763011

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4.3 Biological underpinnings of GrimAge’s and DunedinPACE’s physical activity associations Regarding physical activity, our results showed that weekly physical activity was significantly associated with lower GrimAge AgeDev, whereas daily physical activity did not reach statistical significance.

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