Regarding the relationship between NCC lesion location and regional brain volumes, the temporal lobe showed a nonsignificant trend toward a smaller normalized fraction in participants with lesions (0.2358 vs. 0.2428; Δ = −0.0070; p = 0.0556).
Overall, the only suggestive finding was a possible reduction in temporal lobe volume with lesions, which did not reach statistical significance and should be interpreted with caution; confirmation will require larger and better‐powered samples. 4.
While the MTLE‐HS and MTLE+NCC groups display a slight trend toward smaller volumes, this difference is neither consistent nor statistically significant, suggesting that the findings reflect individual variability rather than a systematic group effect.