METTL3 promotes pancreatic cancer immune escape by m6A modification of lncRNA AFAP1-AS1 to enhance EGR2 stability.

Eur J Med Res · 2026 · PMC12964654 · PMID 41639912

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an increasing trendno p-value reported

AFAP1-AS1 showed an increasing trend with the progression of PAAD tumor stage (stage I-IV) (Fig. 1 G).

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showed a trendno p-value reported

The expression and m6A modification levels of AFAP1-AS1 in PC tissues and cell lines were significantly higher than those of normal controls and showed a trend of increasing with tumor stage progression, and this expression pattern was closely associated with poor patient prognosis.

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