Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen-Like Structures Originating From Retinal Pigment Epithelium.

FASEB J · 2026 · PMC12965378 · PMID 41790486

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Also, the size of the autolysosomes showed a trend towards larger structures in the RPE cells of 5xFAD mice, which can be related to the malfunctioning lysosomal degradation. 3.8.

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