Window of opportunity study measuring defactinib and avutometinib delivery in glioblastomas.

Cancer Chemother Pharmacol · 2026 · PMC12966204 · PMID 41790275

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did not reach statistical significanceno p-value reported

In tumor-adjacent brain tissues, a 4-fold reduction in Erk1/2 phosphorylation was observed with a predicted mean difference of 2.6; however, this did not reach statistical significance.

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