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Left-Right Determination Factor 2 (LEFTY2) Is an Aqueous Humor Biomarker for Exfoliation Glaucoma.

Transl Vis Sci Technol · 2026 · PMC12967114 · PMID 41773776

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LEFTY2 levels were also higher in XFS patients ( x ̄ ± SD = 4.00 ± 4.07 ng/mL; x ̃ = 2.13 ng/mL, IQR = 6.30) relative to controls, although this difference did not reach statistical significance, likely due to the limited XFS sample size (n = 7).

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