Diagnostic and prognostic value of serum markers CEA, CA50, CA19-9, CA72-4, and CYFRA21-1 in colon cancer.

J Med Biochem · 2026 · PMC12967178 · PMID 41799727

Europe PMC DOI

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did not reach statistical significanceP>0.05actually significant

Although differences between specific single-marker and combined detection results did not reach statistical significance (P>0.05), the overall enhancement in diagnostic sensitivity and reliability supports the use of multiplex detection strategies.

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