Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease.

Ann Clin Transl Neurol · 2026 · PMC12968454 · PMID 41089070

Europe PMC DOI

hedged sentence

0.1310

closest p · 2.6× alpha

0.1310

boldest claim

The sentences

did not reach statistical significancep = 0.131not close (p > 0.1)

Carriage of a single ε4 allele was associated with increased TG levels ( p = 0.015, β = 0.157), whereas this association did not reach statistical significance in those carrying double ε4 alleles ( p = 0.131).

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