Prognostic impact of pathological complete response and response-adapted outcomes in patients with gastroesophageal adenocarcinoma treated with neoadjuvant or perioperative treatments: a multicentric cohort study.

ESMO Open · 2026 · PMC12969623 · PMID 41780124

Europe PMC DOI

hedged sentence

0.2000

closest p · 4.0× alpha

0.2000

boldest claim

The sentences

a clear trendP = 0.2not close (p > 0.1)

In the pPR group (TRG 1b/2), no statistically significant survival benefit was observed, although a clear trend toward improved outcomes with adjuvant chemotherapy was noted (OS: HR 0.62, DFS: HR 0.61, P = 0.2 for both).

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