showed a trendp = 0.015
Finally, advanced pathological T stage conferred progressively higher hazards: compared with T1, T2 did not significantly affect CSS and OS (HR 0.78, 95% CI 0.34–1.80; P = 0.556, 0.558); T3 showed a trend toward worse CSS (HR 3.47, 95% CI 1.27–9.51; p = 0.015) and a significant worse OS (HR 3.47, 95% CI 1.27–9.52; p = 0.016); Although pT4 disease showed a significant association with survival in the multivariable model (HR 0.21, p < 0.05), the direction of effect was opposite to the expected trend.