In the univariate analysis (Mann-Whitney U test), miR-200c-3p was significantly down expressed in patients with radioiodine-refractory disease ( P = 0.003), while miR-21-5p ( P = 0.083) and miR-31-5p ( P = 0.093) showed a trend toward higher expression in this group.
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MicroRNA signatures associated with radioiodine refractoriness and tumor dedifferentiation in metastatic papillary thyroid carcinoma.
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