Functional recovery of the adult murine hippocampus after cryopreservation by vitrification.

When comparing control slices (n = 14 from 9 mice) with slices postvitrification (n = 23 from 12 mice), the input–output (I–O) curve from the latter preparation showed a trend toward a lower gain in fPSP amplitude with increasing stimulus intensities (50 to 200 μA), leading to a downward deflection of the curve, which reached significance at the maximum response ( Fig. 2 A ).

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