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Tannic Acid Achieves Rapid Scar-Free Corneal Healing by Chelating Excess Copper to Suppress Aberrant LOX-Mediated Fibrosis.

Invest Ophthalmol Vis Sci · 2026 · PMC12974537 · PMID 41789844

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At day 28, the PBS control group displayed pronounced corneal opacity obscuring the underlying iris (haze score = 2.4 ± 0.54), and the rhEGF-treated positive control group exhibited even more pronounced opacity (haze score = 2.8 ± 0.45), although the difference between these two groups did not reach statistical significance ( Fig. 3 D).

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