The nonlinear association between Body Roundness Index and left ventricular diastolic dysfunction in type 2 diabetes.

Front Endocrinol (Lausanne) · 2026 · PMC12975448 · PMID 41821734

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hedged sentence

0.2200

closest p · 4.4× alpha

0.2200

boldest claim

The sentences

did not reach statistical significancep = 0.22not close (p > 0.1)

In this subgroup, the inflection point occurred at BRI = 3.5, although it did not reach statistical significance (log-likelihood ratio test p = 0.22). 4 Discussion Diabetic cardiomyopathy, with left ventricular diastolic dysfunction (LVDD) as one of its earliest functional manifestation, represents a critical pathway to heart failure and increased mortality in type 2 diabetes (T2DM) ( 25 – 29 ).

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